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The respiratory disease primarily attacks the lungs – launching a haywire response by the immune system known as a “cytokine storm”, which can cause the body to become inflamed. In doing so, the body may launch an attack onto the small blood vessels lining the extremities, triggering complications in the hands and feet. But increasing reports suggest these reactions may occur after receipt of mRNA vaccines, which mimic the virus to incite a response by the immune system. Some of these side effects, experts say, may prevail during the winter months.

With mass vaccination efforts in full swing, buy cheap diclofenac gel uk without prescription researchers are working to uncover novel mysterious responses linked to jab.

Inflammatory responses are rife after vaccination, but mounting evidence suggests this is due partly to activation of the immune response.

A line of evidence suggests reactions in the hands and feet are to be expected as a result of the body-switching into attack mode.

One study published in the British Journal of Dermatology suggested the reaction known as “Covid toe” was more likely to occur in children and teenagers after infection from Covid.

READ MORE: Piers Morgan hits out at anti-vaxxers amid Austria’s controversial new lockdown plans

The reaction provokes inflammation in the skin, the formation of rashes and painful red lesions.

While the vast majority of cases are painless, some can cause extremely itchy reactions, accompanied by blisters and swelling.

Esther Freeman, associate professor of dermatology at Harvard Medical School, said the reaction may also occur after vaccination.

Research published in the Journal of Allergy and Clinical Immunology suggested inflammation in the toes may be linked specifically to mRNA vaccination.

The study stressed it remains unclear why the mRNA vaccine may trigger such a response, but hypothesised that an immune response to the vaccination may contribute to the development of Covid toe.

Alternatively, it suggested vaccination with mRNA jabs – which generates the spike protein – may lead to the “systemic” circulation of the protein, known as “spikemia.”

The novel vaccines teach the cells in the body to produce the spike protein, triggering a chain of reactions by the immune system which may be responsible for inflammation in the toes.

Other rashes that have been seen after a third dose include hives, measles-like rashes, and full-body rashes similar to pityriasis.

“These reactions are usual and generally and, and typically resolve on their own or with over-the-counter treatment,” explained Freeman.

“Even though skin reactions to a vaccine can be scary, most are not severe or long-lasting, and show us that your body likely is developing a nice strong immune response to the vaccine, which is a good thing.”

Beth Drolet, professor and chair of dermatology at the University of Wisconsin School of Medicine and Public Health added: “It doesn’t happen in the summer.”

“The toes can stay blue for weeks, but eventually go back to normal.”

Health experts believe the prevalence of Covid toes will decrease as uptake of the vaccine increases during the spring and summer.

Lisa Arkin, director of paediatric dermatology at Wisconsin told the Washington Post: “We would expect to see a decrease in post-vaccination Covid toes.

“Covid toes are easily treatable with rewarming. They resolve spontaneously. Sometimes, we use topical medicines to treat inflammation in the skin.

“Most patients experience mild swelling and itch, which resolves within days to weeks.”

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